An inexpensive new malaria vaccine is reportedly 80% effective in preventing malaria.

Although it is comparatively inexpensive, 200 million doses will still cost 2 billion dollars to make and administer in Africa.

Malaria can't continue to exist in a mosquito for longer than a mosquito's short life span. If we can prevent it in humans, we can get rid of it entirely — if we can overcome vaccine denialism. There is a lot of vagueness in "80% protective," so I don't know whether this vaccine could eventually eradicate malaria over time. Perhaps in combination with modern genetic engineering that can greatly reduce the mosquito population in an area.